State-backed vaccine maker China National Biotec Group (CNBG) is hopeful of two of its novel coronavirus vaccine candidates receiving conditional regulatory approval for general public use within the year, its vice president said on Tuesday.

China has inoculated hundreds of thousands of people under an emergency programme authorised in July for essential workers and other limited groups of people considered at high risk of infection, to stave off a resurgence of the coronavirus, even as clinical trials of vaccines are still underway to prove their efficacy and safety.

Inoculating the general public with a workable vaccine is likely to be an important tool in curbing a virus that has led to over 960,000 deaths worldwide. However, expanding vaccine use prior to obtaining long-term data risks raising expert concern.

“CNBG is discussing with relevant state authorities about the requirements for conditional approvals of the two coronavirus vaccines,” Zhang Yuntao told Reuters.

The South China Morning Post first reported CNBG’s talks with regulators.

“If all goes well, the two vaccines could hopefully be approved conditionally within the year for use in the general public,” Zhang said in a statement to Reuters.

https://www.reuters.com/article/us-health-coronavirus-cnbg-vaccines/chinese-state-backed-firm-expects-coronavirus-vaccine-approval-for-public-use-within-months-idUSKCN26D0TO

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Hundreds of thousands of people have been given two Chinese COVID-19 vaccine candidates as part of an emergency program, without a single case of infection or adverse effects, a senior official of a state-owned vaccine developer has said.

The two vaccines, developed by China National Biotec Group (CNBG), are expected to enter the market as soon as this December, and two shots will cost less than 1,000 yuan (about 146 U.S. dollars), said Zhou Song, the company's general legal counsel.

They are still undergoing phase three trials for safety and efficacy - usually the last step before regulatory approval - in more than 10 other countries, including the United Arab Emirates, Bahrain, Peru, Morocco, Argentina, and Jordan, since the epidemic has been basically put under control in China.

The two vaccine candidates, together with another one developed by Beijing-based Sinovac, have been approved for civilian emergency use after reliable results in phase one and phase two trials.

https://news.cgtn.com/news/2020-09-11/Hundreds-of-thousands-have-been-given-Chinese-COVID-19-vaccines-THnoo6BcFG/index.html

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China and the United Arab Emirates have seen some positive results in their Phase III COVID-19 vaccine trials, Chinese foreign ministry spokesman Wang Wenbin told a news briefing in Beijing on Wednesday.

The United Arab Emirates on Monday granted emergency approval for use of a coronavirus vaccine, six weeks after human trials in the Gulf Arab state started.

https://www.reuters.com/article/us-health-coronavirus-emirates-vaccine-idUSKBN2670Y0

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Chinese people will have access to locally developed coronavirus vaccines as early as November or December, according to a top scientist from the Chinese Centre for Disease Control and Prevention (CDC).

Clinical trials of several vaccine candidates had been progressing smoothly and preparations were being made to go into mass production, Wu Guizhen, the CDC’s chief biosafety expert, said in a programme shown on Monday night by state broadcaster CCTV.

“I joined the experimental group and had a coronavirus shot in April,” Wu said. “I’ve felt quite good in the past few months, nothing abnormal. The process of inoculation did not cause any localised pain.”

According to the World Health Organisation (WHO), more than 30 vaccine candidates are undergoing clinical trials around the world. Of the nine to have reached the final, phase three, stage, five were developed in China.

Wu said she was optimistic about the vaccine candidates’ efficacy and safety.

“We expect them to remain effective for one to three years … [but] the results will need to be observed for a longer time.”

https://www.scmp.com/news/china/society/article/3101632/coronavirus-chinese-vaccine-ready-use-november-top-scientist

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Domestic air travel in Wuhan, the epicenter of the global coronavirus outbreak, has returned to pre-pandemic levels, authorities say.

The virus was first detected in Wuhan late last year and the city underwent a draconian 76-day lockdown as its hospitals struggled to deal with a tidal wave of cases that required the rapid construction of field hospitals to handle the overflow.

Since re-opening in early April, life has gradually returned to normal and numbers of domestic flights serving the city, as well as the number of passengers, had both fully recovered, according to the operator of Wuhan Tianhe International airport. It said 64,700 passengers were transported aboard 500 domestic flights on Friday.

The airport is preparing to eventually resume international passenger flights to destinations such as Seoul, Singapore, Kuala Lumpur and Jakarta, Qu Xiaoni, an airport representative was quoted as saying by the official Xinhua News Agency.

International cargo routes have already re-opened connecting the major industrial city and center of the Chinese auto industry with destinations such as Amsterdam and New Delhi.

China has gone almost a month without registering a new case of local transmission and on Sunday, the National Health Commission reported just 10 new cases, all of them imported.

https://apnews.com/453e6ba3bf9a4747326d6c1008300452

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Clinical trials in Brazil of a Chinese-made vaccine against Covid-19 have shown “extremely positive” results, and a widespread vaccination campaign could begin as early as December, the governor of Sao Paulo state said on Wednesday.

Sao Paulo, the epicentre of the coronavirus pandemic in hard-hit Brazil, is one of six states helping to test the so-called CoronaVac vaccine developed by Chinese pharmaceutical firm Sinovac Biotech.

The vaccine produced an immune response in 98 per cent of recipients over 60 years old, with no adverse side-effects reported so far, said Governor Joao Doria.

“The results have been extremely positive,” he told a news conference. “We will soon be able to immunise Brazilians in Sao Paulo and across the country with the CoronaVac vaccine … The projected delivery date is in December this year.”

https://www.scmp.com/news/world/americas/article/3100930/brazil-could-launch-chinese-coronavirus-vaccine-year-says

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Mainland China reported two new COVID-19 cases on Sept. 8, down from 10 a day earlier, the country’s national health authority said on Wednesday.

The National Health Commission said in a statement that both cases were imported infections involving travellers from overseas, marking the 24th straight day of no local infections.

The number of new asymptomatic cases also fell to eight from 13 reported a day earlier. China does not count these symptomless patients as confirmed COVID-19 cases.

https://www.reuters.com/article/us-health-coronavirus-china-cases/china-reports-two-new-covid-19-cases-vs-10-a-day-earlier-idUSKBN260004

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Chinese firm Sinovac Biotech Ltd (SVA.O) said on Monday its coronavirus vaccine candidate appeared to be safe for older people, according to preliminary results from an early to mid-stage trial, while the immune responses triggered by the vaccine were slightly weaker than younger adults.

Health officials have been concerned about whether experimental vaccines could safely protect the elderly, whose immune systems usually react less robustly to vaccines, against the virus that has led to nearly 890,000 deaths worldwide.

Sinovac’s candidate CoronaVac did not cause severe side effects in a combined Phase 1 and Phase 2 trials launched in May involving 421 participants aged at least 60, Liu Peicheng, Sinovac’s media representative, told Reuters. The complete results have not been published and were not made available to Reuters.

https://www.reuters.com/article/us-health-coronavirus-vaccine-sinovac/chinas-sinovac-coronavirus-vaccine-candidate-appears-safe-slightly-weaker-in-elderly-idUSKBN25Y1QM

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People in China are shedding their face masks and partying again, with bars, nightclubs and beach venues across the country filling up after months of pandemic controls.

Last weekend, hundreds of Beijing residents attended a music festival on the beachfront at Beidaihe — a location that also serves as the annual getaway for the Communist Party leadership.

To get into the venue, partygoers had to scan their government-designed app that tracks were they have visited, and have their temperatures taken. But once inside the sealed-off resort, they could throw off any thoughts of coronavirus.

“Nobody was wearing masks. It was like we’d all entered a parallel universe and forgot the existence of the epidemic,” said Nancy Lee, 33, an art curator who was one of the festival-goers. “After suffocating at home for more than six months, it was time to loosen up.”

In the capital Beijing, bars and restaurants are becoming busy again. Revellers say they feel they have earned the “freedom to party” after months of strict social distancing from late January.

https://www.ft.com/content/548e151d-39ae-4c6d-9241-b36c3de687b0

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Students in face masks returned to class Tuesday in Wuhan, the central Chinese city where the coronavirus first emerged last year, as the city opened schools and kindergartens for the first time in seven months.

Nearly 1.4 million students resumed classes at some 2,800 kindergartens, primary and middle schools across the city, following the re-opening of high schools in May.

State media broadcast images of thousands of students hoisting the Chinese flag -- a daily routine at all public schools -- despite warnings to avoid mass gatherings.

Schools have drawn up plans to switch back to online teaching should new outbreaks emerge, city officials said last week.

https://www.indiatoday.in/world/story/wuhan-ground-zero-for-coronavirus-epidemic-reopens-all-schools-1717444-2020-09-01

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